I always gear mine as heavy as possible (without sacrifising acceleration in 6th gear) for extended road-use, to keep the revs down.
Also, it sucks to ride in the rpm range where the ypvs opens and closes.
I have 520 sprockets, so they dont compare to the stocker. But 16/49sounds a bit like a 520 conversion? 16/59 is about stock as I recall, so going down 10 teeth in stock size is a big step if thats what you've done
Stock gearing is actually quite good for a bit of everything.
I wouldnt run mine at 8000rpms day ina nd day out, but the bike will probably handle it just fine